Parthenolide has apoptotic and cytotoxic selective effect on B-chronic lymphocytic leukemia cells

Effect of IL-27 on activity of bone marrow NK cells of patient with B-chronic lymphocytic leukemia in vitro

Introduction: Functional defect in immune cells is the prominent feature in hematological malignancies that lead to the expansion of tumor cells. Using immunostimulatory cytokines is one of the new therapeutic approaches. This study aimed to investigate the effect of IL-27 on the activity of bone marrow-NK cells of chronic lymphocytic leukemia (CLL) patients in vitro. Materials and Methods: 10 ...

anti-mutagenic and pro-apoptotic effects of apigenin on human chronic lymphocytic leukemia cells

diet can play a vital role in cancer prevention. nowadays the scientists are looking for food materials which can potentially prevent the cancer occurrence. the purpose of this research is to examine anti-mutagenic and apoptotic effects of apigenin in human lymphoma cells. in present study human chronic lymphocytic leukemia (eheb cell line) were cultured in rpmi 1640 (sigma), supplemented with ...

Chronic Lymphocytic Leukemia B Cells Are Resistant to the Apoptotic Effects of Transforming Growth Factor-b

Chronic lymphocytic leukemia (CLL) is the most common apoptosis, CLL B-cell proliferation was variably inhibited leukemia of the western world and is characterized by a with addition of TGF-b. In vitro addition of IL-4, previously slowly progressing accumulation of clonal CD5 B cells. Our reported to promote CLL B-cell survival, dramatically relaboratory has investigated the role of transformin...

Expression of myelomonocytic antigens on chronic lymphocytic leukemia B cells.

We analyzed the expression of myelomonocytic-associated antigens on lymphocytes from B cell chronic lymphocytic leukemia (B-Cu) patients. Blood mononuclear cells were depleted of monocytes by one-step Percoll density gradient centrifugation and tested for antigen expression by fluorescent microscopy and flow cytometry. The reactivity of patient lymphocytes was as follows: 26 of 31 were positive...

Leukemia Lymphocytic on Leukemic B Cells in Chronic Effect of CD3/CD28 Bead-Activated T Cells